I have been so hesitant to discuss this topic. But Stephen and I agreed that if After Hours is where science gets personal, then we have to be open to have a discussion on sensitive topics, like weight and weight loss.
GLP-1 drugs like Ozempic and Wegovy are having a moment right now. And I get it. As a scientist, it’s fascinating. You’re essentially altering how the body perceives energy, dialing down appetite by shifting hormonal signals around glucose. But what most people don’t realise is that this isn’t just a “shortcut,” it’s a long-term biological commitment. It’s expensive, it requires injections, and it fundamentally changes how your body interacts with food. For someone with Type 2 diabetes or severe obesity, this can be life-changing, even life-saving. In those cases, it’s not about aesthetics, it’s about survival.
But when we start using the same tool to lose the last five kilos, that’s where I pause. Because now we’re not solving a medical problem, we’re outsourcing discipline. And the trade-offs are real: nutrient deficiencies, muscle loss, that hollowed “Ozempic face,” and often the weight comes back the moment you stop.
What I always come back to is this: your body isn’t broken, it’s responding. If you can walk consistently, eat real food, and build habits that your biology recognises, you’re not just losing weight, you’re building a system that lasts. Skinny is easy. Healthy is earned.
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